Illinois Fighting Illini 2020-2021 Schedule
| Date | Opponent | Result |
| 11/25/20 | North Carolina A&T | W 122-60 |
| 11/26/20 | Chicago State | W 97-38 |
| 11/27/20 | Ohio | W 77-75 |
| 12/02/20 | Baylor (Neutral) | L 69-82 |
| 12/05/20 | UT Martin | Postponed |
| 12/08/20 | @ Duke | W 83-68 |
| 12/12/20 | @ Missouri | L 78-81 |
| 12/15/20 | Minnesota | W 92-65 |
| 12/20/20 | @ Rutgers | L 88-91 |
| 12/23/20 | @ Penn State | W 98-81 |
| 12/26/20 | Indiana | W 69-60 |
| 1/02/21 | Purdue | W 66-58 |
| 1/07/21 | @ Northwestern | W 81-56 |
| 1/10/21 | Maryland | L 63-66 |
| 1/13/21 | @ Nebraska | Postponed |
| 1/16/21 | Ohio State | L 81-87 |
| 1/20/21 | Penn State | W 79-65 |
| 1/23/21 | @ Michigan State | Postponed |
| 1/29/21 | Iowa | |
| 2/02/21 | @ Indiana | |
| 2/06/21 | Wisconsin | |
| 2/11/21 | @ Michigan | |
| 2/16/21 | Northwestern | |
| 2/20/21 | @ Minnesota | |
| 2/24/21 | Nebraska | |
| 2/27/21 | @ Wisconsin | |
| 3/06/21 | @ Ohio State |